Senior Director Biomarker Discovery, Translational Sciences

Senior Director Biomarker Discovery, Translational Sciences

3 days ago Be among the first 25 applicantsThis job is with GSK, an inclusive employer and a member of myGwork – the largest global platform for the LGBTQ+ business community. Please do not contact the recruiter directly.

Reporting to Vice President of Translational Sciences, Respiratory, Immunology and Inflammation Translational Unit (RIITU), the

Senior Director, Biomarker Discovery, Translational Sciences

will be responsible for leading laboratory teams in RIITU, delivering innovation in biomarker discovery, ensuring biomarkers are developed for transition to clinical biomarker teams as well generating experimental data to support translational evidence at disease and clinical asset level. A key aspect of this role will be to further develop biomarker insights from high-dimensional omics and genetic approaches generated in the teams at GSK and bring this insight into biomarker innovation and development.

The successful candidate will work closely with the other members of the RIITU leadership team and the overarching research unit leadership teams, GSK matrix and external partners and will represent RIITU at governance level.

Key Responsibilities

Translational Biomarker Discovery Leadership:Lead, inspire, and scale a high-performing Biomarker discovery and assay team of -20 scientists across US and UK, creating a culture of scientific rigor, innovation, and continuous improvement. Mentor and empower team members to reach their full potential, fostering a collaborative environment that maximizes the team''s collective impact on GSK''s RandD objectives.Oversee the biomarker assay development supporting translational science and biomarker discovery, ensuring operational excellence across assay development, context-of-use validation, and sample analysis.Drive the alignment with the biomarker assay group in Development organization on assay platforms and quality expectations to ensure successful assay transitions from preclinical and translational science to clinical study support.Drive the adoption of cutting-edge technologies and methodologies in biomarker identification and measurements; implement new approaches to enhance the quality and throughput of biomarker assays through the application of insights from resources such as the Human Cell Atlas, disease tissue multi-omics data and genetic resources (external or proprietary).Disease Biomarker Strategy Development:Partner with the Disease Teams, Research Technologies and the Development organisation to identify, establish disease biomarkers for decision making throughout clinical development phases and aligned with the overall research and development goals. This will include the identification, prioritisation and validation of disease relevant biomarkers, mechanistic/surrogate biomarkers, patient stratification, and differentiated response prediction through to their deployment into clinical studies.Cross-functional Collaboration:Collaborate closely with cross-functional teams including the Translational, Disease Teams, Human Genetics and Genomics, biology groups, biomarker platforms, Medicine Development Teams, HBSM , data-sciences, regulatory affairs, business development and commercial to ensure seamless integration of translational research and biomarker strategies across the drug development lifecycle.External Partnerships:Establish and maintain strategic collaborations with academic institutions, contract research organizations (CROs), and other external partners to access cutting-edge technologies, tools, reagents, biosamples, biomarker expertise, and research capabilities.Foster a network of external experts and key opinion leaders to stay at the forefront of translational science and biomarker advancements across the industry.Contribute to evaluation and diligence of business development opportunities.Matrix Leadership:Provide mentorship, guidance, and professional development opportunities to ensure a high-performing and motivated team.Manage disease and project level resources, budgets, and timelines to ensure the successful execution of projects and achievement of milestones and RIITU objectives.

Why you?

Basic Qualifications

We are looking for professionals with these required skills to achieve our goals:

Ph.D. in a relevant scientific discipline (e.g., Cell/Molecular Biology, Genetics, Pharmacology, Physical Chemistry or related field)Extensive experience in translational science and biomarker development within the pharmaceutical or biotechnology industry with broad knowledge in technologies and methods used in translational research.Recognised translational biomarker expert in scientific community through publications and contributions to the field.Track record of developing novel biomarkers working with multi-omics evidenceKnowledge of regulatory requirements, industry standards, best practices and compliance considerations in Translational Research and biomarker development and validation.Broad knowledge in technologies and methods used in translational research.Proven track record of program decision making through implementing biomarker strategies and delivering translational science insights in support of drug progression through clinical transition milestones.Experience leading/managing external collaborations and evaluation of business development opportunities.Strong executive management skills, with the ability to prioritize and manage multiple projects to meet timelines while maintaining attention to detail and high-performance standards.Excellent inclusive matrix leadership skills, with the ability to create psychological safety, inspire and motivate a team towards achieving common goals.Ability to adapt to a fast-paced and evolving research environment, with strong problem-solving and critical-thinking skills.

Preferred Qualifications

If you have the following characteristics, it would be a plus:

Awareness of bioinformatic / computational methods supporting integrated analysis and interpretation of translational and biomarker-related data sets.

Work Location:

This role is based in the United Kingdom or United States and will require on-site presence with flexibility for hybrid working arrangements.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a special purpose - to unite science, technology and talent to get ahead of disease together - so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns - as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology).

Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it''s also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves - feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.

Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on UKRecruitment.Adjustments@gsk.com or 0808 234 4391. The helpline is available from 8.30am to 12.00 noon Monday to Friday, during bank holidays these times and days may vary.

Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a UK Recruitment FAQ guide. Click the link and scroll to the Careers Section where you will find answers to multiple questions we receive

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK''s commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK''s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/Seniority level

Seniority level DirectorEmployment type

Employment type Full-timeJob function

Job function Research, Analyst, and Information TechnologyIndustries Pharmaceutical ManufacturingReferrals increase your chances of interviewing at myGwork - LGBTQ+ Business Community by 2xGet notified about new Science Director jobs in

Stevenage, England, United Kingdom .Director of Product Management - Protein Science

Cambridge, England, United Kingdom 3 weeks agoStevenage, England, United Kingdom 3 days agoSenior Director, Respiratory Biology - IPF and ILD

Senior Director of Product Management, Research Solutions

Haynes, England, United Kingdom 6 days agoDirector, Danaher Operating Company Strategic Partnerships

Cambridge, England, United Kingdom 3 weeks agoDirector Therapeutic Area Portfolio Analytics - Respiratory and Immunology

Cambridge, England, United Kingdom 2 days agoExecutive Director, Oncology Early Clinical Development Lead - Heme

Stevenage, England, United Kingdom 6 days agoCambridge, England, United Kingdom 1 week agoAssociate Director, Real World Evidence (Remote)

Cambridge, England, United Kingdom 2 weeks agoExecutive Director, Oncology Early Clinical Development Lead - GU/Prostate

Cambridge, England, United Kingdom 1 week agoCentral Bedfordshire, England, United Kingdom 3 weeks agoClinical Professorship and Director, CRUK Cambridge Centre

Cambridge, England, United Kingdom 3 weeks agoDirector Therapeutic Area Portfolio Analytics

Cambridge, England, United Kingdom 3 days agoClinical Professorship and Director, CRUK Cambridge Centre

Cambridge, England, United Kingdom 1 week agoCambridge, England, United Kingdom 1 month agoContracts - Experienced Regulatory Affairs Professionals - Manager to Director L

Cambridge, England, United Kingdom 1 month agoAmersham, England, United Kingdom 1 week agoSenior Director Biomarker Discovery, Translational Sciences

Stevenage, England, United Kingdom 3 days agoHinxton, England, United Kingdom 2 weeks agoCambridge, England, United Kingdom 3 weeks agoSenior Associate or Associate Director - Electrical

Cambridge, England, United Kingdom 5 days agoWe’re unlocking community knowledge in a new way. Experts add insights directly into each article, started with the help of AI.

#J-18808-Ljbffr